This article is part of our NFL Game Previews series.
Seattle (+6) at San Francisco, 46.5 o/u – Monday, 8:15 p.m. EST
For the record, my little jury-rigged formula for determining margin of victory matched the spread for the first time all year (Niners by six... 6.3, if you want to get nit-picky), so if this one ends up a push, don't say you weren't warned. Seattle needs a win here if they want to have any chance of winning the NFC West. A San Francisco win puts them 2.5 games up, and they'd have to completely collapse down the stretch to allow the Seahawks back in it. Fortunately, Russell Wilson is playing like a guy who can beat any team, any time, any where, and last week's overtime heroics against the Bucs were just par for the course for the QB this season. His second-worst YPA in a game this season is 8.1, and his 22:1 TD:INT through nine contests is simply incredible. Even the banged-up state of his offensive line doesn't seem to be an impediment. Wilson now gets his toughest test yet in the Niners, although that's also true the other way. They're second to the Pats in basically every major passing category other than yards per game allowed (where they're in first), and while they haven't faced quite the list of scrub QBs the Pats have, their most impressive conquests have come against the likes of Jared Goff and Jameis Winston. The epic clash between Wilson and the Richard Sherman-led secondary will take center
